The effects of young and aged, male and female megakaryocyte conditioned media on angiogenic properties of endothelial cells

Murad K. Nazzal, Hanisha L. Battina, Nikhil P. Tewari, Sarah L. Mostardo, Rohit U. Nagaraj, Donghui Zhou, Olatundun D. Awosanya, Saveda K. Majety, Sue Samson, Rachel J. Blosser, Ushashi C. Dadwal, Patrick L. Mulcrone, Melissa A. Kacena · 2024

Read The effects of young and aged, male and female megakaryocyte conditioned media on angiogenic properties of endothelial cells by Murad K. Nazzal, Hanisha L. Battina, Nikhil P. Tewari, Sarah L. Mostardo, Rohit U. Nagaraj, Donghui Zhou, Olatundun D. Awosanya, Saveda K. Majety, Sue Samson, Rachel J. Blosser, Ushashi C. Dadwal, Patrick L. Mulcrone, Melissa A. Kacena (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11719103.txt.

Description

Murad Nazzal and co-authors test how fluids from blood forming cells affect vessel growth by age and sex in 2024. New vessels aid bone healing, which slows with age. The cells studied make platelets and release growth factors. Fluids were gathered from the cells of young and old mice, male and female. They were fed to vessel cells from bone marrow.

Female cell fluid boosted vessel cell growth at both ages. Young male fluid raised vessel form a lot. Old male fluid raised some vessel traits but cut vessel counts versus young male fluid. Old female fluid sped cell movement hugely, yet wound closure fell with old fluids. Gene levels in vessel cells shifted with treatment. The work may guide new ways to aid bone repair in older people.

Catalog record

CREATORMurad K. Nazzal, Hanisha L. Battina, Nikhil P. Tewari, Sarah L. Mostardo, Rohit U. Nagaraj, Donghui Zhou, Olatundun D. Awosanya, Saveda K. Majety, Sue Samson, Rachel J. Blosser, Ushashi C. Dadwal, Patrick L. Mulcrone, Melissa A. Kacena
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE45 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11719103

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