A Comparative Study of Nalbuphine, Clonidine, and Dexmedetomidine as Adjuvants to Ropivacaine in Epidural Anesthesia for Lower Limb Surgery

Usha Shukla, Manoj Kumar, Deepanshu Panchal, Deepika Doneria · 2024

Read A Comparative Study of Nalbuphine, Clonidine, and Dexmedetomidine as Adjuvants to Ropivacaine in Epidural Anesthesia for Lower Limb Surgery by Usha Shukla, Manoj Kumar, Deepanshu Panchal, Deepika Doneria (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11718113.txt.

Description

Usha Shukla, Manoj Kumar, Deepanshu Panchal, and Deepika Doneria compare three drugs added to a local anesthetic in epidural anesthesia for leg surgery. Added drugs can make the block start faster, last longer, and ease pain afterward. Patients were randomly split into three groups, each getting a different addition.

The dexmedetomidine group had the fastest start of both feeling and movement block, and by far the longest block and pain relief. Nalbuphine came next, and clonidine last, though clonidine caused more slow heart rate, low blood pressure, nausea, and vomiting. Sedation was most common with dexmedetomidine but stayed manageable. The authors rank dexmedetomidine first among the three.

Catalog record

CREATORUsha Shukla, Manoj Kumar, Deepanshu Panchal, Deepika Doneria
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE32 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11718113

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