The potential of plasma TDP‐43 as a biomarker for limbic predominant age related TDP‐43 encephalopathy
Lorena Sordo, Anne‐Marie C Leiby, Rond Malhas, James Barlow, Robert A Rissman, Claudia H Kawas, María M M Corrada, Elizabeth Head, S Ahmad Sajjadi · 2025
Read The potential of plasma TDP‐43 as a biomarker for limbic predominant age related TDP‐43 encephalopathy by Lorena Sordo, Anne‐Marie C Leiby, Rond Malhas, James Barlow, Robert A Rissman, Claudia H Kawas, María M M Corrada, Elizabeth Head, S Ahmad Sajjadi (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11716964.txt.
Description
Lorena Sordo and co-authors test, in a 2025 pilot study, whether a protein in blood could flag a common age-related brain condition called LATE. The condition involves build-up of the TDP-43 protein in memory regions of very old brains, and no blood test for it exists yet.
The team measured the protein in blood from forty-eight people whose brains were later checked after death. Just over half had the condition at a clear stage. The test read the protein in every sample, though some noisy results were dropped. The work is a first step toward telling this condition apart from Alzheimer's disease during life.
Catalog record
| CREATOR | Lorena Sordo, Anne‐Marie C Leiby, Rond Malhas, James Barlow, Robert A Rissman, Claudia H Kawas, María M M Corrada, Elizabeth Head, S Ahmad Sajjadi |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 2 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |