Identification of high‐performance blood‐based biomarkers for early screening and staging of Alzheimer’s disease by large‐scale plasma proteomic profiling in mild cognitive impairments
Yuanbing JIANG, Hyebin Uhm, Fanny C. F. Ip, Ronnie M.N. Lo, Xiaoyun Cao, Clara M.C. Tan, Brian C.H. Law, Timothy CY Kwok, Vincent Chung Tong Mok, Henrik Zetterberg, Amy K.Y. Fu, Nancy Y. Ip · 2025
Read Identification of high‐performance blood‐based biomarkers for early screening and staging of Alzheimer’s disease by large‐scale plasma proteomic profiling in mild cognitive impairments by Yuanbing JIANG, Hyebin Uhm, Fanny C. F. Ip, Ronnie M.N. Lo, Xiaoyun Cao, Clara M.C. Tan, Brian C.H. Law, Timothy CY Kwok, Vincent Chung Tong Mok, Henrik Zetterberg, Amy K.Y. Fu, Nancy Y. Ip (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11716945.txt.
Description
Yuanbing Jiang and co-authors search in 2025 for blood markers that can screen and stage Alzheimer disease early. Current tests lean on thinking checks, costly scans, or spinal fluid, each with limits. Blood tests would be cheaper and gentler for wide screening.
The team measured more than one thousand proteins in blood from a Hong Kong cohort with mild memory loss. Near five hundred proteins differed from healthy patterns, in varied body processes and with distinct shift shapes. A marker panel built from those finds was checked in a second group sorted by brain scans. The panel aims to catch disease at the mild stage and track its phase.
Catalog record
| CREATOR | Yuanbing JIANG, Hyebin Uhm, Fanny C. F. Ip, Ronnie M.N. Lo, Xiaoyun Cao, Clara M.C. Tan, Brian C.H. Law, Timothy CY Kwok, Vincent Chung Tong Mok, Henrik Zetterberg, Amy K.Y. Fu, Nancy Y. Ip |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 2 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |