Compression and expansion in the aging brain is associated with clinical and cognitive outcomes
Jenna N Adams, Yuritza Y Escalante, Michael A Yassa, Niels Janssen · 2025
Read Compression and expansion in the aging brain is associated with clinical and cognitive outcomes by Jenna N Adams, Yuritza Y Escalante, Michael A Yassa, Niels Janssen (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11716935.txt.
Description
Jenna Adams and co-authors study, in a 2025 paper, how the whole shape of the brain changes with age. Rather than looking at single regions alone, they track where the surface of the brain presses inward and where it stretches outward, and how the two sides drift apart.
The team worked with more than two thousand scans from adults aged forty-two to ninety-seven. Shape measures were compared across age groups and against a rating of clinical impairment. The authors also checked how shape change lined up with scores on thinking tests. Their approach treats aging as a change in the brain's overall form, not just shrinkage in a few spots.
Catalog record
| CREATOR | Jenna N Adams, Yuritza Y Escalante, Michael A Yassa, Niels Janssen |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |