Long‐term exposure to non‐steroidal anti‐inflammatory (NSAID) medication in relation to dementia risk: a population‐based cohort study
Ilse vom Hofe, Bruno H. Stricker, M. Kamran Ikram, Frank J. Wolters, M. Arfan Ikram · 2025
Read Long‐term exposure to non‐steroidal anti‐inflammatory (NSAID) medication in relation to dementia risk: a population‐based cohort study by Ilse vom Hofe, Bruno H. Stricker, M. Kamran Ikram, Frank J. Wolters, M. Arfan Ikram (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11716850.txt.
Description
Ilse vom Hofe and co-authors test whether long use of common anti-inflammatory pain drugs links to lower dementia risk. Such drugs might calm brain inflammation and cut amyloid buildup. Past studies disagree, and dose patterns were rarely clear.
The Rotterdam cohort held thousands of dementia-free adults at entry. Pharmacy records tracked drug use across decades of follow-up. Total duration sorted users into none, short, medium, and long use. Models adjusted for lifestyle, illness, and other medicines. Dementia onset was tracked into recent years. Time-varying methods handled changing exposure over the years. The study sharpens the duration question for prevention research. Its scale and records give the answer weight.
Catalog record
| CREATOR | Ilse vom Hofe, Bruno H. Stricker, M. Kamran Ikram, Frank J. Wolters, M. Arfan Ikram |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 2 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |