A novel amyloid MRI imaging based on analysis of texture features representing Aß aggregation
Yasuko Tatewaki, Hitoshi Yamagata, Benjamin Thyreau, Tetsuya Yoneda, Taizen Nakase, Momoka Asato, Tatsuo Nagasaka, Naoki Kaneko, Jason Hinman, Yasuyuki Taki · 2025
Read A novel amyloid MRI imaging based on analysis of texture features representing Aß aggregation by Yasuko Tatewaki, Hitoshi Yamagata, Benjamin Thyreau, Tetsuya Yoneda, Taizen Nakase, Momoka Asato, Tatsuo Nagasaka, Naoki Kaneko, Jason Hinman, Yasuyuki Taki (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11716846.txt.
Description
Yasuko Tatewaki and nine co-authors test whether ordinary MRI can be taught to show the amyloid plaques of Alzheimer's disease, in this 2025 study. Detecting amyloid early matters more now that a drug slowing the disease exists. The standard test, a PET scan, is costly and scarce. MRI is cheaper and everywhere, but no one had shown it could reveal amyloid.
Amyloid clumps gather iron, and iron disturbs the phase signal in certain MRI scans. The team built a texture analysis of that phase signal from a special multi-echo scan, producing what they call amyloid MRI. They tested it on forty-eight memory clinic patients, average age seventy-two, who had both MRI and PET scans. Thirty were amyloid-positive by PET. Comparing the new images against that gold standard shows whether a routine scanner can shoulder a job now reserved for PET.
Catalog record
| CREATOR | Yasuko Tatewaki, Hitoshi Yamagata, Benjamin Thyreau, Tetsuya Yoneda, Taizen Nakase, Momoka Asato, Tatsuo Nagasaka, Naoki Kaneko, Jason Hinman, Yasuyuki Taki |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 2 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |