Direct comparisons of the associations between the tau PET tracers [18F]Flortaucipir and [18F]MK6240 with tests of general cognitive performance ‐ The HEAD study
Livia Amaral, Guilherme Povala, Bruna Bellaver, Guilherme Bauer‐Negrini, Firoza Z Lussier, Pamela C.L. Ferreira, Juli Cehula, Dana Tudorascu, William J. Jagust, William E Klunk, Val J. Lowe, Hwamee Oh, David N. soleimani‐meigooni, Belen Pascual, Brian A. Gordon, Pedro Rosa‐Neto, Suzanne L. Baker, Th · 2025
Read Direct comparisons of the associations between the tau PET tracers [18F]Flortaucipir and [18F]MK6240 with tests of general cognitive performance ‐ The HEAD study by Livia Amaral, Guilherme Povala, Bruna Bellaver, Guilherme Bauer‐Negrini, Firoza Z Lussier, Pamela C.L. Ferreira, Juli Cehula, Dana Tudorascu, William J. Jagust, William E Klunk, Val J. Lowe, Hwamee Oh, David N. soleimani‐meigooni, Belen Pascual, Brian A. Gordon, Pedro Rosa‐Neto, Suzanne L. Baker, Th (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11716828.txt.
Description
Livia Amaral and a large team of co-authors published a study in 2025 comparing two tracers used to image tau in the living brain. Both tracers stick to tau tangles, but they differ in strength and precision. The team asked which one's signal tracks thinking scores more closely in the same people.
They studied 170 adults, most with normal thinking and the rest impaired, who had scans with both tracers. Each person also took standard tests of memory and overall function. The researchers compared tracer signals region by region against those scores, adjusting for age, sex, and schooling. Head-to-head data like this helps trials pick the better tool for tracking disease.
Catalog record
| CREATOR | Livia Amaral, Guilherme Povala, Bruna Bellaver, Guilherme Bauer‐Negrini, Firoza Z Lussier, Pamela C.L. Ferreira, Juli Cehula, Dana Tudorascu, William J. Jagust, William E Klunk, Val J. Lowe, Hwamee Oh, David N. soleimani‐meigooni, Belen Pascual, Brian A. Gordon, Pedro Rosa‐Neto, Suzanne L. Baker, Th |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |