Salivary biomarkers for the molecular diagnosis of Dementia with Lewy Bodies
Fabrizia D'Antonio, Giorgio Vivacqua, Marco Serrentino, Martyna Podgajna, Aleksandra Kaczynska, Martina Peconi, Maria Ilenia De Bartolo, Massimiliano Panigutti, Micaela Sepe‐Monti, Giuseppina Talarico, Giovanni Fabbrini, Giuseppe Bruno · 2025
Read Salivary biomarkers for the molecular diagnosis of Dementia with Lewy Bodies by Fabrizia D'Antonio, Giorgio Vivacqua, Marco Serrentino, Martyna Podgajna, Aleksandra Kaczynska, Martina Peconi, Maria Ilenia De Bartolo, Massimiliano Panigutti, Micaela Sepe‐Monti, Giuseppina Talarico, Giovanni Fabbrini, Giuseppe Bruno (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11716801.txt.
Description
D'Antonio and co-authors test saliva as a diagnostic fluid for Lewy body dementia in a 2025 study. The disease is the second most common nerve dementia, yet it is often missed and no firm test exists. The team measured forms of two proteins, alpha-synuclein and tau, in saliva from four small groups: patients with Lewy body, Alzheimer's, or Parkinson's disease, plus healthy peers.
One synuclein form split Lewy body patients from Parkinson's patients and from healthy peers. Clumped synuclein ran high in all patient groups. A changed tau form ran high in Lewy body and Alzheimer's groups and tracked thinking decline. The authors call the saliva marks a promising early lead, pending larger checks.
Catalog record
| CREATOR | Fabrizia D'Antonio, Giorgio Vivacqua, Marco Serrentino, Martyna Podgajna, Aleksandra Kaczynska, Martina Peconi, Maria Ilenia De Bartolo, Massimiliano Panigutti, Micaela Sepe‐Monti, Giuseppina Talarico, Giovanni Fabbrini, Giuseppe Bruno |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 2 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |