Multimodal intervention for risk reduction of dementia in older adults with type 2 diabetes: Post‐hoc sub‐group analyses of the J‐MINT

Taiki Sugimoto, Kazuaki Uchida, Nanae Matsumoto, Kosuke Fujita, Yoko Yokoyama, Yujiro Kuroda, Takuya Omura, Akinori Nakamura, Paul K. Crane, Hidenori Arai, Takashi Sakurai, J‐MINT study group · 2025

Read Multimodal intervention for risk reduction of dementia in older adults with type 2 diabetes: Post‐hoc sub‐group analyses of the J‐MINT by Taiki Sugimoto, Kazuaki Uchida, Nanae Matsumoto, Kosuke Fujita, Yoko Yokoyama, Yujiro Kuroda, Takuya Omura, Akinori Nakamura, Paul K. Crane, Hidenori Arai, Takashi Sakurai, J‐MINT study group (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11716800.txt.

Description

Taiki Sugimoto and co-authors revisited, in a 2025 analysis, a Japanese dementia prevention trial to ask whether its program helped participants who also had type 2 diabetes. The J-MINT trial ran eighteen months with older adults who had mild cognitive deficits. Its program combined blood vessel risk control, exercise, nutrition advice, and brain training against a control arm receiving written health tips.

Of 531 enrollees, 76 had diabetes. The team split them by age band, memory status, blood sugar control against national targets, and a genetic risk marker. Thinking scores were tracked as a blend of memory, attention, and speed tests. The subgroup lens checks whether a broad lifestyle program pays off evenly, or only for some patients. Such answers guide who should be offered scarce program places first.

Catalog record

CREATORTaiki Sugimoto, Kazuaki Uchida, Nanae Matsumoto, Kosuke Fujita, Yoko Yokoyama, Yujiro Kuroda, Takuya Omura, Akinori Nakamura, Paul K. Crane, Hidenori Arai, Takashi Sakurai, J‐MINT study group
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE3 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11716800

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