Unique Pattern of White Matter Hyperintensities in Middle Age and Older Adults with History of Repetitive Head Impact Exposure

Jenna R. Groh, Annalise E. Miner, Chad Farris, Yorghos Tripodis, Christopher J. Nowinski, Anna Cui, Erika C. Pettway, Fatima Tuz‐Zahra, Mohamad J. Alshikho, Adam M. Brickman, Steven Lenio, Monica T. Ly, Caroline Altaras, Andrew E. Budson, Katherine W. Turk, Wendy Qiu, Lee E Goldstein, Brett Martin, · 2025

Read Unique Pattern of White Matter Hyperintensities in Middle Age and Older Adults with History of Repetitive Head Impact Exposure by Jenna R. Groh, Annalise E. Miner, Chad Farris, Yorghos Tripodis, Christopher J. Nowinski, Anna Cui, Erika C. Pettway, Fatima Tuz‐Zahra, Mohamad J. Alshikho, Adam M. Brickman, Steven Lenio, Monica T. Ly, Caroline Altaras, Andrew E. Budson, Katherine W. Turk, Wendy Qiu, Lee E Goldstein, Brett Martin, (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11716799.txt.

Description

Jenna Groh and co-authors map a distinct pattern of brain white matter spots in a 2025 study. Repeated head impacts from contact sports can injure white matter, showing as bright spots on a kind of MRI scan. The team compared seventy-six adults, half with heavy past exposure to such impacts and half with little or none.

Clinicians judged the exposed group to carry a greater load of the spots. More years of American football play raised the odds of a moderate to severe load. The exposed group also had more small, round spots close to the brain's outer layer, clustered near groove depths. That pattern differs from spots caused by vessel disease or inflammation, the authors say.

Catalog record

CREATORJenna R. Groh, Annalise E. Miner, Chad Farris, Yorghos Tripodis, Christopher J. Nowinski, Anna Cui, Erika C. Pettway, Fatima Tuz‐Zahra, Mohamad J. Alshikho, Adam M. Brickman, Steven Lenio, Monica T. Ly, Caroline Altaras, Andrew E. Budson, Katherine W. Turk, Wendy Qiu, Lee E Goldstein, Brett Martin,
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE3 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11716799

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