Differences between white matter hyperintensities lesion load across allostatic load risk in cognitive complaint subjects
Patricio Riquelme Contreras, Fernando Henriquez, Cecilia Gonzalez Campo, Ingrid Buller‐Peralta, Daniela Thumala, Patricia Lillo, Cecilia Okuma, Michele Demanet, María Francisca Damm, Claudio Román Godoy, Pamela Guevara Alvez, El‐Deredy Wael, Graciela Muniz‐Terrera, Andrea Slachevsky Chonchol · 2025
Read Differences between white matter hyperintensities lesion load across allostatic load risk in cognitive complaint subjects by Patricio Riquelme Contreras, Fernando Henriquez, Cecilia Gonzalez Campo, Ingrid Buller‐Peralta, Daniela Thumala, Patricia Lillo, Cecilia Okuma, Michele Demanet, María Francisca Damm, Claudio Román Godoy, Pamela Guevara Alvez, El‐Deredy Wael, Graciela Muniz‐Terrera, Andrea Slachevsky Chonchol (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11716769.txt.
Description
Patricio Riquelme Contreras and co-authors link chronic stress load to white matter damage in a study from 2025. Allostatic load tallies the body's wear from long stress. White matter hyperintensities, bright spots on brain scans, mark small vessel disease and early decay. Whether stress wear feeds those spots was the question.
The cohort held one hundred thirty-five Chilean adults with memory complaints. A standard cognition test helped sort them by stress risk level. Scan software measured bright spot volume tract by tract. Three risk tiers showed distinct lesion loads in key tracts. The pattern ties lived stress to a prodromal step toward dementia. Stress care may belong in early brain health plans.
Catalog record
| CREATOR | Patricio Riquelme Contreras, Fernando Henriquez, Cecilia Gonzalez Campo, Ingrid Buller‐Peralta, Daniela Thumala, Patricia Lillo, Cecilia Okuma, Michele Demanet, María Francisca Damm, Claudio Román Godoy, Pamela Guevara Alvez, El‐Deredy Wael, Graciela Muniz‐Terrera, Andrea Slachevsky Chonchol |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |