Differential expression of miRNAs from circulating exosomes in Alzheimer disease and frontotemporal dementia
Paulina Orellana, Ariel Caviedes, Hernan Hernandez, Patricia Lillo, Roque Villagra, Mauricio Cerda, Pedro Zitko, Daniela Thumala, Christian Gonzalez‐Billault, Agustin Ibañez, Rolando de la Cruz, Andrea Slachevsky Chonchol, Claudia Duran‐Aniotz · 2025
Read Differential expression of miRNAs from circulating exosomes in Alzheimer disease and frontotemporal dementia by Paulina Orellana, Ariel Caviedes, Hernan Hernandez, Patricia Lillo, Roque Villagra, Mauricio Cerda, Pedro Zitko, Daniela Thumala, Christian Gonzalez‐Billault, Agustin Ibañez, Rolando de la Cruz, Andrea Slachevsky Chonchol, Claudia Duran‐Aniotz (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11716767.txt.
Description
Paulina Orellana and co-authors hunt blood marks in 2025 that split two dementias which mimic each other. Alzheimer disease and frontotemporal dementia ask for different care, and blood tests for either are scarce. Tiny parcels shed by cells into blood carry small RNAs whose levels shift with disease.
Plasma parcels came from twenty-five healthy controls, twenty-five Alzheimer patients, and ten frontotemporal patients in Chile, the team reports. Their small RNAs were read and fed to learning models that sort the groups. Marks found in parcels could one day make the split with a simple blood draw. That would spare families the long, costly road of scans and spinal taps, and start the right care sooner.
Catalog record
| CREATOR | Paulina Orellana, Ariel Caviedes, Hernan Hernandez, Patricia Lillo, Roque Villagra, Mauricio Cerda, Pedro Zitko, Daniela Thumala, Christian Gonzalez‐Billault, Agustin Ibañez, Rolando de la Cruz, Andrea Slachevsky Chonchol, Claudia Duran‐Aniotz |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 2 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |