Association of pulsatility of lenticulostriate arteries with cognitive decline in elderly adults: a 7T dual‐VENC PC‐MRI study
Jianing Tang, Tianrui Zhao, Elizabeth B Joe, Helena C Chui, Lirong Yan · 2025
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Description
Jianing Tang and colleagues linked pulsatility in tiny brain arteries to cognitive decline in older adults. Their 2025 study used ultra-high-field 7T MRI scanning. Small vessel disease is a major cause of vascular dementia. The lenticulostriate arteries feeding deep brain tissue are central suspects. A pulsatility index captures how stiffly blood pulses through them.
Twenty-five elderly participants joined the imaging study. Cognitive screening used two standard bedside tests. Pulsatility rose with age and with fewer years of schooling. Higher pulsatility tracked with lower scores on one cognitive test. The other test showed the same trend without reaching significance. Direct measures of these small arteries may flag dementia risk early. The findings tie vessel dysfunction to failing cognition.
Catalog record
| CREATOR | Jianing Tang, Tianrui Zhao, Elizabeth B Joe, Helena C Chui, Lirong Yan |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |