Higher cardiorespiratory fitness is associated with higher cerebral myelination in normative aging
Mary E Faulkner, Zhaoyuan Gong, Murat Bilgel, John P Laporte, Alex Guo, Jonghyun Bae, Palchamy Elango, Christopher M Bergeron, Mustapha Bouhrara · 2025
Read Higher cardiorespiratory fitness is associated with higher cerebral myelination in normative aging by Mary E Faulkner, Zhaoyuan Gong, Murat Bilgel, John P Laporte, Alex Guo, Jonghyun Bae, Palchamy Elango, Christopher M Bergeron, Mustapha Bouhrara (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11716569.txt.
Description
Mary E Faulkner and eight co-authors published a study in 2025 on fitness and the brain's insulation in healthy aging. Nerve fibers are wrapped in myelin, a fatty coating that speeds signals and thins with age. The team asked whether people with fitter hearts and lungs keep more of that coating.
They studied 110 healthy adults aged twenty-two to ninety-four from two aging studies. Each person took a maximal treadmill test and had a special MRI scan that maps myelin across the brain. Higher fitness went with higher myelin content in white matter regions. The link mattered across the adult lifespan. Keeping fit may be one way to protect the wiring of the aging brain.
Catalog record
| CREATOR | Mary E Faulkner, Zhaoyuan Gong, Murat Bilgel, John P Laporte, Alex Guo, Jonghyun Bae, Palchamy Elango, Christopher M Bergeron, Mustapha Bouhrara |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |