Plasma p217+tau accurately discriminates Intermediate or Advanced Alzheimer's Disease biological PET stages

Azadeh Feizpour, Vincent Dore, Natasha Krishnadas, Pierrick Bourgeat, James D Doecke, Ziad S Saad, Gallen Triana‐Baltzer, Simon M Laws, Rosita Shishegar, Kun Huang, Christopher J Fowler, Larry Ward, Colin L Masters, Jurgen Fripp, Hartmuth C Kolb, Victor L Villemagne, Christopher C Rowe · 2025

Read Plasma p217+tau accurately discriminates Intermediate or Advanced Alzheimer's Disease biological PET stages by Azadeh Feizpour, Vincent Dore, Natasha Krishnadas, Pierrick Bourgeat, James D Doecke, Ziad S Saad, Gallen Triana‐Baltzer, Simon M Laws, Rosita Shishegar, Kun Huang, Christopher J Fowler, Larry Ward, Colin L Masters, Jurgen Fripp, Hartmuth C Kolb, Victor L Villemagne, Christopher C Rowe (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11716550.txt.

Description

Azadeh Feizpour and a large team of co-authors published a study in 2025 on whether a blood test can stage Alzheimer's disease as well as brain scans do. Scans sort patients into stages from initial to advanced, which guides treatment choices. A blood marker that mirrors those stages would be far easier to use.

They studied 475 adults, a mix of healthy and impaired, who had blood tests plus amyloid and tau scans. The blood marker rose steadily across scan stages, apart from the two earliest, which it could not separate. It screened for intermediate and advanced stages with strong accuracy. Staging by blood draw may soon spare many patients two scans.

Catalog record

CREATORAzadeh Feizpour, Vincent Dore, Natasha Krishnadas, Pierrick Bourgeat, James D Doecke, Ziad S Saad, Gallen Triana‐Baltzer, Simon M Laws, Rosita Shishegar, Kun Huang, Christopher J Fowler, Larry Ward, Colin L Masters, Jurgen Fripp, Hartmuth C Kolb, Victor L Villemagne, Christopher C Rowe
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE2 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11716550

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