Lower plasma p‐tau levels and larger hippocampi may protect African American SuperAgers from age‐related cognitive decline and Alzheimer’s disease
Wiktoria Piaszczynska, Miray Budak, Bernadette A. Fausto, Payton G. White, Robert Perna, Patricia Fitzgerald‐Bocarsly, Fanyu Hercules Tawe, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg, Mark A. Gluck · 2025
Read Lower plasma p‐tau levels and larger hippocampi may protect African American SuperAgers from age‐related cognitive decline and Alzheimer’s disease by Wiktoria Piaszczynska, Miray Budak, Bernadette A. Fausto, Payton G. White, Robert Perna, Patricia Fitzgerald‐Bocarsly, Fanyu Hercules Tawe, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg, Mark A. Gluck (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11716548.txt.
Description
Some older adults keep a sharp memory well past the age when most peers fade. Wiktoria Piaszczynska and ten co-authors study such SuperAgers among African Americans, a group often left out of aging research. Their 2025 work draws on a long-running study of healthy aging in the region.
The team compares brain scans and blood tests between SuperAgers and typical peers of the same age. They look at the size of parts of the hippocampus, a brain area key to memory, and at blood levels of a tau form tied to early Alzheimer's disease. Early signs point to lower tau levels and larger memory areas in the SuperAger group. The work hints at what may shield the mind as years pass.
Catalog record
| CREATOR | Wiktoria Piaszczynska, Miray Budak, Bernadette A. Fausto, Payton G. White, Robert Perna, Patricia Fitzgerald‐Bocarsly, Fanyu Hercules Tawe, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg, Mark A. Gluck |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 2 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |