Comparison of amyloid positron emission tomography, hippocampal volume, and plasma biomarkers in predicting conversion to mild cognitive impairment
Murat Bilgel, Yang An, Ishaan Shah, Keenan A Walker, Abhay Moghekar, Nicholas J Ashton, Przemyslaw Radoslaw Kac, Thomas K Karikari, Kaj Blennow, Henrik Zetterberg, Madhav Thambisetty, Susan M Resnick · 2025
Read Comparison of amyloid positron emission tomography, hippocampal volume, and plasma biomarkers in predicting conversion to mild cognitive impairment by Murat Bilgel, Yang An, Ishaan Shah, Keenan A Walker, Abhay Moghekar, Nicholas J Ashton, Przemyslaw Radoslaw Kac, Thomas K Karikari, Kaj Blennow, Henrik Zetterberg, Madhav Thambisetty, Susan M Resnick (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11716537.txt.
Description
Murat Bilgel and eleven co-authors published a study in 2025 on which early signs best predict a slide into mild memory loss. Doctors can scan the brain for amyloid, measure a memory-related brain area, or test blood for several markers. The team compared how well each approach flagged people who later developed mild cognitive impairment.
They followed 178 healthy adults in a long-running aging study in Baltimore, of whom 33 later developed the condition. Each marker was tested in models that also accounted for age, sex, race, and schooling. The study helps doctors judge which tests give the most warning before symptoms begin. Blood tests are far cheaper than brain scans, so how they compare matters for screening plans.
Catalog record
| CREATOR | Murat Bilgel, Yang An, Ishaan Shah, Keenan A Walker, Abhay Moghekar, Nicholas J Ashton, Przemyslaw Radoslaw Kac, Thomas K Karikari, Kaj Blennow, Henrik Zetterberg, Madhav Thambisetty, Susan M Resnick |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |