Coronary artery calcium and Alzheimer’s Disease biomarkers in cognitively unimpaired adults
Sofia Marcolini, Jaime Mondragon, Rozemarijn Vliegenthart, Charlotte Teunissen, Inge MW Verberk, Ronald JH Borra, Rudi Dierckx, Peter Paul De Deyn · 2025
Read Coronary artery calcium and Alzheimer’s Disease biomarkers in cognitively unimpaired adults by Sofia Marcolini, Jaime Mondragon, Rozemarijn Vliegenthart, Charlotte Teunissen, Inge MW Verberk, Ronald JH Borra, Rudi Dierckx, Peter Paul De Deyn (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11716494.txt.
Description
Sofia Marcolini and co-authors compare heart artery calcium with Alzheimer's biomarkers in healthy adults in a 2025 study. Calcified coronary plaque marks silent atherosclerosis and has been tied, inconsistently, to cognition. Its link to the disease's molecular markers had never been analyzed.
About two hundred eighty-five adults over fifty with normal cognition came from a Dutch population cohort. Heart scans sorted them into no calcium and elevated calcium groups. Cognitive tests and Alzheimer's biomarkers were then compared across the groups. If vessel burden tracks the brain's earliest changes, heart scans could one day help time dementia prevention.
Catalog record
| CREATOR | Sofia Marcolini, Jaime Mondragon, Rozemarijn Vliegenthart, Charlotte Teunissen, Inge MW Verberk, Ronald JH Borra, Rudi Dierckx, Peter Paul De Deyn |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |