Differential effects of sex on hippocampal volume and cortical thickness in a racially and ethnically diverse cohort across the Alzheimer’s disease continuum
Taylor F Levine, Jessica ZK Caldwell · 2025
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Description
Women's brains may resist Alzheimer's shrinkage for a while, then lose ground, a pattern seen mostly in white study samples. Taylor Levine and Jessica Caldwell tested whether that story holds in a diverse cohort in 2025, spanning the Alzheimer's continuum.
Data came from a Texas health and aging study with about eight hundred non-Hispanic white, 470 Black American, and 713 Mexican American participants. The team measured hippocampus size and cortical thickness against a blood marker of amyloid. Among white participants, healthy women showed no link between the marker and hippocampus size, a sign of resilience, matching earlier work. The study asks whether the same shield appears, or fails to, in the other groups.
Catalog record
| CREATOR | Taylor F Levine, Jessica ZK Caldwell |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |