Association of cardiorespiratory fitness with dementia risk across different levels of genetic predisposition: a large community‐based longitudinal study
Shuqi Wang, Liyao Xu, Wenzhe Yang, Jiao Wang, Abigail Dove, Xiuying Qi, Weili Xu · 2025
Read Association of cardiorespiratory fitness with dementia risk across different levels of genetic predisposition: a large community‐based longitudinal study by Shuqi Wang, Liyao Xu, Wenzhe Yang, Jiao Wang, Abigail Dove, Xiuying Qi, Weili Xu (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11716480.txt.
Description
Shuqi Wang and co-authors test whether heart and lung fitness guards against dementia even in people born with high genetic risk, in work from 2025. Fitness reflects how well the heart and lungs supply the body. Its tie to thinking and dementia was unclear.
Over sixty-one thousand dementia free adults in the UK Biobank were followed for up to sixteen years. Fitness was estimated from a six minute bike test and split into low, middle, and high thirds. Thinking tests covered memory of several kinds and speed. The team then asked whether high fitness softened the risk carried by dementia linked genes. A modifiable shield would matter most for those at highest inherited risk.
Catalog record
| CREATOR | Shuqi Wang, Liyao Xu, Wenzhe Yang, Jiao Wang, Abigail Dove, Xiuying Qi, Weili Xu |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |