Association of Retinal Layer Thickness with Brain Volume and Cortical Thickness in older adults
Ji Won Han, Hyeong Min Kim, Min Jeong Kwon, Jieun Park, Jun Sung Kim, Se Joon Woo, Ki Woong Kim · 2025
Read Association of Retinal Layer Thickness with Brain Volume and Cortical Thickness in older adults by Ji Won Han, Hyeong Min Kim, Min Jeong Kwon, Jieun Park, Jun Sung Kim, Se Joon Woo, Ki Woong Kim (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11716452.txt.
Description
Ji Won Han and co-authors linked retinal layer thickness to brain structure in 2025 in older adults. The retina shares tissue origins with the brain, so its nerve layer might mirror brain shrinkage tied to thinking decline. One hundred sixty-six non-demented people over sixty-five had eye scans and brain imaging.
Thicker outer retinal nerve layers matched larger grey matter in three cortical regions, and total thickness matched one of them. Retinal thickness also tracked cortical thickness in several areas, including regions for sensory integration and cognition. After strict correction for many comparisons, the links lost significance. The authors still read the pattern as a biological hint worth pursuing in larger cohorts with cognitive outcomes.
Catalog record
| CREATOR | Ji Won Han, Hyeong Min Kim, Min Jeong Kwon, Jieun Park, Jun Sung Kim, Se Joon Woo, Ki Woong Kim |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 2 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |