Effects of a multi‐domain intervention against cognitive decline on dementia risk profiles – Results from the AgeWell.de‐trial
Andrea Zülke, Alexander Pabst, Melanie Luppa, David Czock, Birgitt Wiese, Wolfgang Hoffmann, Thomas Frese, Jochen Gensichen, Hans‐Helmut König, Hanna Kaduszkiewicz, Jochen René Thyrian, Steffi G. Riedel‐Heller · 2025
Read Effects of a multi‐domain intervention against cognitive decline on dementia risk profiles – Results from the AgeWell.de‐trial by Andrea Zülke, Alexander Pabst, Melanie Luppa, David Czock, Birgitt Wiese, Wolfgang Hoffmann, Thomas Frese, Jochen Gensichen, Hans‐Helmut König, Hanna Kaduszkiewicz, Jochen René Thyrian, Steffi G. Riedel‐Heller (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11716437.txt.
Description
Andrea Zülke and eleven co-authors report, in 2025 work, results from a German trial that coached older adults in many life habits at once. The aim was to slow mind decline and cut dementia risk. Rather than wait for illness, the trial scored risk with an index built from twelve health and habit factors.
More than four hundred adults at raised risk took part, with checks at the start and two years on. The group that got coaching saw its risk score fall by a clear margin. Gains came most from better food choices and lower blood pressure. Younger members also grew more active in mind tasks. Some factors, like lack of exercise, did not move. The team backs the index as a stand-in score for such trials.
Catalog record
| CREATOR | Andrea Zülke, Alexander Pabst, Melanie Luppa, David Czock, Birgitt Wiese, Wolfgang Hoffmann, Thomas Frese, Jochen Gensichen, Hans‐Helmut König, Hanna Kaduszkiewicz, Jochen René Thyrian, Steffi G. Riedel‐Heller |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |