The effect of AD co‐pathology on cognitive phenotype and FDG‐PET patterns in Parkinson’s disease with cognitive impairment

Sandra Castro‐Labrador, Jesús Silva‐Rodríguez, Miguel Labrador‐Espinosa, Laura Muñoz‐Delgado, Pablo Franco‐Rosado, Ana María Castellano Guerrero, Daniel Macías‐García, Silvia Jesús Maestre, Astrid Adarmes‐Gómez, Elena Ojeda‐Lepe, Fátima Carillo, Juan Francisco Martín Rodríguez, San Eufrasio M, Crist · 2025

Read The effect of AD co‐pathology on cognitive phenotype and FDG‐PET patterns in Parkinson’s disease with cognitive impairment by Sandra Castro‐Labrador, Jesús Silva‐Rodríguez, Miguel Labrador‐Espinosa, Laura Muñoz‐Delgado, Pablo Franco‐Rosado, Ana María Castellano Guerrero, Daniel Macías‐García, Silvia Jesús Maestre, Astrid Adarmes‐Gómez, Elena Ojeda‐Lepe, Fátima Carillo, Juan Francisco Martín Rodríguez, San Eufrasio M, Crist (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11716406.txt.

Description

Sandra Castro-Labrador and co-authors asked how Alzheimer's pathology changes thinking in Parkinson's disease, in this 2025 study. Many Parkinson's patients develop thinking problems, and added Alzheimer's change is a known risk. A blood marker can now flag that added pathology.

The team studied 88 Parkinson's patients, half with thinking problems and half without. Blood tests split the impaired group by marker status. About 28 percent of the impaired group carried the marker, versus 13 percent of the unimpaired group. Brain fuel-use scans and thinking profiles were compared across groups. The study shows the blood marker can sort patients whose decline may follow a mixed path.

Catalog record

CREATORSandra Castro‐Labrador, Jesús Silva‐Rodríguez, Miguel Labrador‐Espinosa, Laura Muñoz‐Delgado, Pablo Franco‐Rosado, Ana María Castellano Guerrero, Daniel Macías‐García, Silvia Jesús Maestre, Astrid Adarmes‐Gómez, Elena Ojeda‐Lepe, Fátima Carillo, Juan Francisco Martín Rodríguez, San Eufrasio M, Crist
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE3 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11716406

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