Differences in protein expression in Alzheimer’s disease patients based on risk factors for amyloid‐related imaging abnormalities
Marlies Oosthoek, Lisa Vermunt, Elena Raluca Blujdea, Sjors G.J.G. in 't Veld, Wiesje M. van der Flier, Frederik Barkhof, Marta del Campo, Martín Pucheu Avilés, Allerdien Visser, Martijn C. Schut, Everard G.B. Vijverberg, Charlotte Teunissen · 2025
Read Differences in protein expression in Alzheimer’s disease patients based on risk factors for amyloid‐related imaging abnormalities by Marlies Oosthoek, Lisa Vermunt, Elena Raluca Blujdea, Sjors G.J.G. in 't Veld, Wiesje M. van der Flier, Frederik Barkhof, Marta del Campo, Martín Pucheu Avilés, Allerdien Visser, Martijn C. Schut, Everard G.B. Vijverberg, Charlotte Teunissen (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11716379.txt.
Description
Marlies Oosthoek and co-authors report a 2025 study on blood and spine fluid proteins and a known risk in Alzheimer's care. Some new drugs for the disease can cause odd spots on brain scans, grouped under one short name. Risk is higher in people with small bleeds in the brain, a gene form, or low levels of a plaque protein.
The team read 288 proteins in spine fluid from 156 people with the disease. They split people by each risk trait and by a high risk and low risk mix. Each split showed its own set of changed proteins, and most were lower in the high risk group. The sets barely overlapped, which hints that each risk trait works in its own way.
Catalog record
| CREATOR | Marlies Oosthoek, Lisa Vermunt, Elena Raluca Blujdea, Sjors G.J.G. in 't Veld, Wiesje M. van der Flier, Frederik Barkhof, Marta del Campo, Martín Pucheu Avilés, Allerdien Visser, Martijn C. Schut, Everard G.B. Vijverberg, Charlotte Teunissen |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |