Distinct Spatial Patterns for White Matter Microstructure Changes in an Aging and Alzheimer’s Disease Cohort
Jianqiao Tian, Sheelakumari Raghavan, Petrice M Cogswell, Robert I. Reid, Scott A. Przybelski, Christopher G. Schwarz, Jonathan Graff‐Radford, Val J. Lowe, Kejal Kantarci, David S. Knopman, Ronald C. Petersen, Clifford R. Jack, Prashanthi Vemuri · 2025
Read Distinct Spatial Patterns for White Matter Microstructure Changes in an Aging and Alzheimer’s Disease Cohort by Jianqiao Tian, Sheelakumari Raghavan, Petrice M Cogswell, Robert I. Reid, Scott A. Przybelski, Christopher G. Schwarz, Jonathan Graff‐Radford, Val J. Lowe, Kejal Kantarci, David S. Knopman, Ronald C. Petersen, Clifford R. Jack, Prashanthi Vemuri (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11716372.txt.
Description
Jianqiao Tian leads a team in a 2025 study of white matter change in aging and Alzheimer's disease, with a hunt for distinct spatial patterns. Harm to white matter, the brain's wiring, comes with vessel and nerve diseases and feeds poor thinking. The team held that more than one path of change may run at once.
A clustering tool for subtype and stage was run on rich diffusion MRI data. Two read-outs grade the wires: how dense the fibers are packed, and how much free water sits in the tissue. The maps then show if aging and disease split into clear patterns in space.
Catalog record
| CREATOR | Jianqiao Tian, Sheelakumari Raghavan, Petrice M Cogswell, Robert I. Reid, Scott A. Przybelski, Christopher G. Schwarz, Jonathan Graff‐Radford, Val J. Lowe, Kejal Kantarci, David S. Knopman, Ronald C. Petersen, Clifford R. Jack, Prashanthi Vemuri |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |