Rostral locus coeruleus metabolism relates to Alzheimer's disease pathology and cognition in amyloid‐positive symptomatic individuals
Elouise A Koops, Joyita Dutta, Alex Becker, Bernard J Hanseeuw, Reisa A Sperling, Keith A Johnson, Heidi IL Jacobs · 2025
Read Rostral locus coeruleus metabolism relates to Alzheimer's disease pathology and cognition in amyloid‐positive symptomatic individuals by Elouise A Koops, Joyita Dutta, Alex Becker, Bernard J Hanseeuw, Reisa A Sperling, Keith A Johnson, Heidi IL Jacobs (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11716266.txt.
Description
Elouise A Koops and co-authors report a 2025 brain scan study on a small deep brain area and Alzheimer's disease. The area, called the locus coeruleus, helps control alert states and sends a key chemical through the brain. The team asked how hard this area works in people who test positive for the disease plaques.
The study used scans from 78 people with memory loss who were in a large shared study group. A new scan method let the team split the small area into front, middle, and back parts. The front part worked harder in people with more of the tau protein tied to the disease. That hard work also linked to faster growth of tau over time.
Catalog record
| CREATOR | Elouise A Koops, Joyita Dutta, Alex Becker, Bernard J Hanseeuw, Reisa A Sperling, Keith A Johnson, Heidi IL Jacobs |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |