CSF ATN and α‐synuclein co‐pathology in AD, PD, and DLB
Marianna Rizzo, Charlotte Teunissen, Henrik Zetterberg, Kaj Blennow, Gwendlyn Kollmorgen, Nancy Ramia, Rejko Krüger, Olga Borejko, Dag Aarsland, Michele Hu, Thomas Klockgether, Kathrin Brockmann, Thomas Gasser, Frank Jessen, Annika Spottke, Wiesje M. van der Flier, Afina Willemina Lemstra, Betty M. · 2025
Read CSF ATN and α‐synuclein co‐pathology in AD, PD, and DLB by Marianna Rizzo, Charlotte Teunissen, Henrik Zetterberg, Kaj Blennow, Gwendlyn Kollmorgen, Nancy Ramia, Rejko Krüger, Olga Borejko, Dag Aarsland, Michele Hu, Thomas Klockgether, Kathrin Brockmann, Thomas Gasser, Frank Jessen, Annika Spottke, Wiesje M. van der Flier, Afina Willemina Lemstra, Betty M. (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11716245.txt.
Description
Rizzo and co-authors compare in 2025 spinal fluid markers across Alzheimer's disease, Parkinson's disease, and Lewy body dementia. Mixed pathology among these diseases is poorly understood, yet it shapes trial design. The study drew 337 people from six centers, including healthy controls.
Fluid measures covered amyloid, tau, nerve damage, and a synuclein protein tied to the other two diseases. The Alzheimer's group was the largest, at 170 people. Models adjusted for age and sex, and the team asked which traits sway amyloid status. Shared markers across diagnoses would change how patients are grouped for trials and care.
Catalog record
| CREATOR | Marianna Rizzo, Charlotte Teunissen, Henrik Zetterberg, Kaj Blennow, Gwendlyn Kollmorgen, Nancy Ramia, Rejko Krüger, Olga Borejko, Dag Aarsland, Michele Hu, Thomas Klockgether, Kathrin Brockmann, Thomas Gasser, Frank Jessen, Annika Spottke, Wiesje M. van der Flier, Afina Willemina Lemstra, Betty M. |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |