Psychosis in Alzheimer’s Disease

Clive G Ballard · 2025

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Description

Clive Ballard reviews psychosis in Alzheimer's disease. It is a common and upsetting feature of the illness, and no treatment is approved for it. Delusions and hallucinations in these patients track with worse outcomes and a higher chance of moving into care. New criteria now help doctors spot the condition. In some patients, the signs show up even before memory problems appear.

The review looks at fresh work on genes and brain scans. It also looks at post-mortem tissue, and at how this work sharpens ideas about how the symptoms arise. Drugs that may help include pimavanserin, which is licensed in the United States for psychosis in Parkinson's disease. Other options are escitalopram, muscarinic agonists, and cannabidiol. Ballard also covers better targeted talking therapies. He covers the harder problem of psychosis in related dementias, and the near lack of work on vascular dementia.

Catalog record

CREATORClive G Ballard
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE2 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11716220

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