Digital speech markers of cognitive impairment in ALS‐FTD spectrum disorders
Sanjana Shellikeri, Sunghye Cho, Sharon Ash, Carmen Gonzalez‐Recober, Katheryn A Q Cousins, Corey T McMillan, Lauren Elman, Colin Quinn, Defne A Amado, Michael Baer, David J Irwin, Lauren Massimo, Mark Y Liberman, Naomi Nevler · 2025
Read Digital speech markers of cognitive impairment in ALS‐FTD spectrum disorders by Sanjana Shellikeri, Sunghye Cho, Sharon Ash, Carmen Gonzalez‐Recober, Katheryn A Q Cousins, Corey T McMillan, Lauren Elman, Colin Quinn, Defne A Amado, Michael Baer, David J Irwin, Lauren Massimo, Mark Y Liberman, Naomi Nevler (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11716208.txt.
Description
Sanjana Shellikeri and co-authors study speech as a sign of thinking problems in ALS in a 2025 paper. Some people with this motor disease also develop dementia or language loss, and standard tests need trained staff. The team instead recorded patients describing a picture and let a computer measure the speech. They compared several patient groups across the ALS and frontotemporal dementia spectrum.
The study covered 51 people with ALS, 22 with ALS plus frontotemporal dementia, and 12 with milder cognitive changes. The dementia group differed on twelve speech measures, including slower speech, more pauses, and fewer describing words. Three measures together separated the dementia group from plain ALS with strong accuracy. Repeat recordings let the team track how speech changed over time within the same person.
Catalog record
| CREATOR | Sanjana Shellikeri, Sunghye Cho, Sharon Ash, Carmen Gonzalez‐Recober, Katheryn A Q Cousins, Corey T McMillan, Lauren Elman, Colin Quinn, Defne A Amado, Michael Baer, David J Irwin, Lauren Massimo, Mark Y Liberman, Naomi Nevler |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |