Impact of Grey Matter Volume and White Matter Hyperintensities on Functional Capacity for Activities of Daily Living: A Study in the Alzheimer's Disease Continuum
Cecilia Gonzalez Campo, Fernando Henriquez, Patricio Riquelme Contreras, Patricia Lillo, David Martínez‐Pernía, Daniela Thumala, Francisco Aboitiz, Andrea Slachevsky Chonchol, Rodrigo Henriquez · 2025
Read Impact of Grey Matter Volume and White Matter Hyperintensities on Functional Capacity for Activities of Daily Living: A Study in the Alzheimer's Disease Continuum by Cecilia Gonzalez Campo, Fernando Henriquez, Patricio Riquelme Contreras, Patricia Lillo, David Martínez‐Pernía, Daniela Thumala, Francisco Aboitiz, Andrea Slachevsky Chonchol, Rodrigo Henriquez (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11716189.txt.
Description
Cecilia Gonzalez Campo and co-authors ask in 2025 which brain changes steal daily function along the Alzheimer path. Gray matter shrinkage and white matter bright spots on scans both track with worse thinking and daily skills. The study grouped 130 matched adults across subjective decline, mild impairment, and dementia.
Daily function was scored with a technology-based questionnaire, brain volume by morphometry, and white matter lesions split by location. The dementia group managed daily tasks worst, with less gray matter and more lesions near the ventricles. The analysis weighs which scan measure, volume or lesion load and place, best explains lost function.
Catalog record
| CREATOR | Cecilia Gonzalez Campo, Fernando Henriquez, Patricio Riquelme Contreras, Patricia Lillo, David Martínez‐Pernía, Daniela Thumala, Francisco Aboitiz, Andrea Slachevsky Chonchol, Rodrigo Henriquez |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |