Association of sleep network functional connectivity with hyperexcitability and cognition in Alzheimer’s disease
Sebastian Moguilner, Courtney Berezuk, Alex C Bender, Kyle R Pellerin, Stephen Gomperts, Sydney Cash, Rani A Sarkis, Alice D Lam · 2025
Read Association of sleep network functional connectivity with hyperexcitability and cognition in Alzheimer’s disease by Sebastian Moguilner, Courtney Berezuk, Alex C Bender, Kyle R Pellerin, Stephen Gomperts, Sydney Cash, Rani A Sarkis, Alice D Lam (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11716164.txt.
Description
Sebastian Moguilner and co-authors published this study in two thousand twenty-five on sleep, brain wiring, and overactive brain signals in Alzheimer's disease. Poor sleep is common early in the disease, and bursts of excess brain activity during sleep can harm memory.
The team recorded brain waves at home for three groups: healthy older adults, people with early Alzheimer's, and people with Alzheimer's who also had epilepsy. They measured how brain areas linked up during each sleep stage. The Alzheimer's groups showed clear shifts in those links, and the epilepsy group had its own pattern. Some link measures tracked who lost thinking ground fastest over time. Machine learning sorted the groups well from sleep and waking data alike. The authors say sleep wiring could help doctors track the disease and find treatment targets.
Catalog record
| CREATOR | Sebastian Moguilner, Courtney Berezuk, Alex C Bender, Kyle R Pellerin, Stephen Gomperts, Sydney Cash, Rani A Sarkis, Alice D Lam |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 2 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |