Research Lumbar Puncture Recruitment, Safety and SOPs in Black/African American and white middle‐age participants
Kelly D S Likos, William T Hu, Danielle D Verble, Lynn Marie Trotti, Karima Benameur, Laura M Scorr, Brittany Butts, Whitney Wharton · 2025
Read Research Lumbar Puncture Recruitment, Safety and SOPs in Black/African American and white middle‐age participants by Kelly D S Likos, William T Hu, Danielle D Verble, Lynn Marie Trotti, Karima Benameur, Laura M Scorr, Brittany Butts, Whitney Wharton (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11716119.txt.
Description
Kelly Likos and co-authors report that volunteers for Alzheimer's research will accept the spinal tap, repeatedly, and that this holds across race. Fluid drawn from the spine is among the most informative samples in Alzheimer's science. Yet many studies skip it, fearing refusals and side effects. Extra doubt is often cast on minority recruitment. Their 2025 paper lays out a decade of practice in one laboratory.
The current cohort holds 122 cognitively normal, middle-aged adults with a parent who had the disease. Twenty milliliters are drawn by drip or aspiration. The team phones the next day, and daily after, until any side effects fade. The data show the procedures are safe and well tolerated, and that participants agree to multiple taps regardless of race, ethnicity, or gender. The authors publish their standard procedures hoping to retire that assumption.
Catalog record
| CREATOR | Kelly D S Likos, William T Hu, Danielle D Verble, Lynn Marie Trotti, Karima Benameur, Laura M Scorr, Brittany Butts, Whitney Wharton |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |