Discovery and preclinical development of [18F]ACI‐19626, a first‐in‐class TDP‐43 PET tracer

Tamara Seredenina · 2025

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Description

Tamara Seredenina reports a first of kind scan dye that sticks to TDP-43 clumps in sick brains, in a 2025 report. Those clumps mark a set of nerve ills with no live scan till now. A true dye could sort sick folks and track cures in trials with far more care.

More than five hundred blends screen on sick brain bits for tight grip. The best blend grips clumps hard and skips three rival clump kinds in tests. It also skips two known false pull spots in brain checks. Ape scans show fast brain in and out, fit for live scans. First human tests come next for the dye.

Catalog record

CREATORTamara Seredenina
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE3 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11716116

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