Delayed blood arrival partially mediates the association between arterial dilatation and cerebral small vessel disease
W Hudson Robb, Panpan Zhang, Krish U Shah, Michelle L Houston, Niranjana Shashikumar, Niranjana Shashikumar, Kimberly R Pechman, Dandan Liu, L Taylor Davis, Angela L Jefferson, Timothy J Hohman · 2025
Read Delayed blood arrival partially mediates the association between arterial dilatation and cerebral small vessel disease by W Hudson Robb, Panpan Zhang, Krish U Shah, Michelle L Houston, Niranjana Shashikumar, Niranjana Shashikumar, Kimberly R Pechman, Dandan Liu, L Taylor Davis, Angela L Jefferson, Timothy J Hohman (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11716080.txt.
Description
Robb and co-authors examine in 2025 whether slow blood arrival to the brain helps explain the link between widened brain arteries and small vessel disease. Widening of arteries is tied to higher Alzheimer risk and to more white matter spots on scans, a sign of that disease. The team studied 249 adults in a memory and aging project who began free of dementia or stroke.
Brain scans measured the inner width of two main arteries, the timing of blood arrival, and white matter burden. Arrival timing was higher, meaning slower, in connection with wider arteries. Statistical tests then ask how far slow arrival carries the effect of widening on white matter burden, in line with the study title.
Catalog record
| CREATOR | W Hudson Robb, Panpan Zhang, Krish U Shah, Michelle L Houston, Niranjana Shashikumar, Niranjana Shashikumar, Kimberly R Pechman, Dandan Liu, L Taylor Davis, Angela L Jefferson, Timothy J Hohman |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |