Associations of gray matter volume and white mater hyperintensity mean diffusivity and volume with PiB status in mild cognitive impairment

Tales Santini, Jinghang Li, James E Emanuel, Jr‐Jiun Liou, Andrea Sajewski, Cong Chu, Bruno de Almeida, Brian J Lopresti, Howard J Aizenstein, Minjie Wu, Ariel Gildengers, Tamer S Ibrahim · 2025

Read Associations of gray matter volume and white mater hyperintensity mean diffusivity and volume with PiB status in mild cognitive impairment by Tales Santini, Jinghang Li, James E Emanuel, Jr‐Jiun Liou, Andrea Sajewski, Cong Chu, Bruno de Almeida, Brian J Lopresti, Howard J Aizenstein, Minjie Wu, Ariel Gildengers, Tamer S Ibrahim (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11716065.txt.

Description

Brain scan traits that split amyloid-positive from amyloid-free mild memory loss are weighed by Tales Santini and co-authors in work dated 2025. White spots in the brain mark vessel harm, while amyloid build-up marks early Alzheimer disease. Telling the two apart guides care picks. Seventy-one people with mild loss got amyloid scans and strong-field brain scans.

The amyloid group held smaller memory zones, the hippocampus and amygdala. The amyloid-free group held more white spot bulk, with looser tissue inside the spots. Over a year of follow-up, amyloid-group zones shrank fast. Spot traits may thus flag vessel-led loss.

Catalog record

CREATORTales Santini, Jinghang Li, James E Emanuel, Jr‐Jiun Liou, Andrea Sajewski, Cong Chu, Bruno de Almeida, Brian J Lopresti, Howard J Aizenstein, Minjie Wu, Ariel Gildengers, Tamer S Ibrahim
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE2 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11716065

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