Predicting individual‐level stroke risk associated with risperidone use in dementia using cardiovascular disease history: matched UK population based cohort study
Nalamotse Joshua Choma, Alys Griffiths, William E Henley, Christoph Mueller, Nefyn Williams, John Dennis, Byron Creese · 2025
Read Predicting individual‐level stroke risk associated with risperidone use in dementia using cardiovascular disease history: matched UK population based cohort study by Nalamotse Joshua Choma, Alys Griffiths, William E Henley, Christoph Mueller, Nefyn Williams, John Dennis, Byron Creese (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11716047.txt.
Description
Stroke risk for people with dementia who take risperidone is the target of a 2025 study by Nalamotse Joshua Choma and co-authors. Risperidone is the only drug of its class approved in the United Kingdom for the agitation and aggression that dementia can cause. It also carries a known risk of stroke, so the team wants risk judged person by person.
The project uses records for more than 358,000 patients from a national primary care database. It compares stroke rates in dementia patients who took the drug with those who never did. It then tests whether heart and vessel history changes each person's risk. Those patterns will feed personal prediction models for safer prescribing.
Catalog record
| CREATOR | Nalamotse Joshua Choma, Alys Griffiths, William E Henley, Christoph Mueller, Nefyn Williams, John Dennis, Byron Creese |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |