A novel fMRI memory paradigm designed for brain imaging studies in early Alzheimer’s Disease
Himanshu Joshi, Sivakumar PT, Ganesan Venkatasubramanian, John P John, Paul M Thompson · 2025
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Description
A memory test built for brain scanners is presented in a 2025 study by Himanshu Joshi and co-authors, designed for people in the early stages of Alzheimer's disease. Many scan tasks demand complex instructions, which patients with real memory trouble cannot follow.
The test runs in two seven-minute phases. First, patients simply view common objects, some repeated, without being told to memorize them. Then they see a small set of those objects mixed with new ones and must judge each. The study scanned sixty-five patients with mild impairment or mild disease and twenty-six healthy older adults. Brain activity maps were compared across groups, with age, schooling, and brain size taken into account.
Catalog record
| CREATOR | Himanshu Joshi, Sivakumar PT, Ganesan Venkatasubramanian, John P John, Paul M Thompson |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 2 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |