Differences in cerebrospinal fluid and cerebral blood flow measurements by age, sex, and APOE4 status in older adults

Yilei Dong, Ashwin Sakhare, Joy Stradford, Teresa Monreal, A Lisette Isenberg, Judy Pa · 2025

Read Differences in cerebrospinal fluid and cerebral blood flow measurements by age, sex, and APOE4 status in older adults by Yilei Dong, Ashwin Sakhare, Joy Stradford, Teresa Monreal, A Lisette Isenberg, Judy Pa (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11715987.txt.

Description

Fluid that bathes the brain helps clear waste and move nutrients, and its flow may shift long before memory fails. Yilei Dong and five co-authors measure that flow, and blood flow in the brain, in older adults. Their 2025 study asks how the measures vary by age, sex, and a gene form tied to Alzheimer's disease.

Seventy-nine healthy older adults, drawn from two larger trials, each had a brain scan at the start. A scan method that times flow took readings at a narrow brain channel, at the space around the cord, and in neck arteries. The team then looks for links between flow and each trait. The work helps set a normal range for a system that may matter in early disease.

Catalog record

CREATORYilei Dong, Ashwin Sakhare, Joy Stradford, Teresa Monreal, A Lisette Isenberg, Judy Pa
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE2 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11715987

Browse the full library · About the Tower of Babel