Association between anti‐herpetic medications and dementia risk: A systematic review and meta‐analysis
Syuan‐Ting Chang, Yi‐ Fang Chuang · 2025
Read Association between anti‐herpetic medications and dementia risk: A systematic review and meta‐analysis by Syuan‐Ting Chang, Yi‐ Fang Chuang (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11715927.txt.
Description
Syuan-Ting Chang and Yi-Fang Chuang review whether drugs used against herpes viruses lower the risk of dementia, in this 2025 combined analysis. Herpes infections have been tied to higher dementia risk in past research. If the viruses play a real role, then treating them might protect the brain, an idea the authors test across cohort studies.
Twelve studies covering more than nine and a half million older adults met the review's rules. People who took anti-herpes drugs had lower dementia risk in every comparison the team ran. The cut was largest, about a quarter, among people diagnosed with an infection who received treatment versus those who did not. The benefit looked strongest in severe infections. The authors call the drugs a promising lead, not yet proof of cause.
Catalog record
| CREATOR | Syuan‐Ting Chang, Yi‐ Fang Chuang |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 2 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |