Characterizing White Matter Hyperintensity (WMH) Patterns with Texture‐Based Analysis
Mohamad J. Alshikho, Clarissa Morales, Jeffrey D. Pyne, Erica Amarante, Patrick J. Lao, Indira C. Turney, Natalie C. Edwards, Yian Gu, Jennifer J. Manly, Richard Mayeux, Adam M. Brickman · 2025
Read Characterizing White Matter Hyperintensity (WMH) Patterns with Texture‐Based Analysis by Mohamad J. Alshikho, Clarissa Morales, Jeffrey D. Pyne, Erica Amarante, Patrick J. Lao, Indira C. Turney, Natalie C. Edwards, Yian Gu, Jennifer J. Manly, Richard Mayeux, Adam M. Brickman (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11715924.txt.
Description
Mohamad J Alshikho and ten co-authors published a study in 2025 on reading the texture of bright spots in brain white matter. These spots, seen on MRI scans of older adults, vary in size and brightness because their causes vary, from small vessel disease to inflammation. Lumping them together may hide which kind threatens thinking.
Working with 161 adults from a New York aging project, the team sorted each person's spots into even, middling, and mottled zones by signal texture. They then compared fiber quality and blood flow inside each zone. Fiber and flow measures related differently across zones, with the mottled tissue behaving unlike the smooth. Texture-aware maps could sharpen how doctors judge these common scan findings.
Catalog record
| CREATOR | Mohamad J. Alshikho, Clarissa Morales, Jeffrey D. Pyne, Erica Amarante, Patrick J. Lao, Indira C. Turney, Natalie C. Edwards, Yian Gu, Jennifer J. Manly, Richard Mayeux, Adam M. Brickman |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |