Synergism across neurodegenerative diseases using biological definitions
Kathleen L Poston · 2025
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Description
Kathleen Poston, a solo author, reviews a shift in how brain diseases of aging are defined in a 2025 paper. New biomarker tests can now reveal disease processes in living people, before any symptoms show. Research frameworks for Alzheimer's disease, Huntington's disease, and a group of synuclein diseases have begun to define each illness by its biology rather than by its outward syndrome.
Poston draws out what the shared shift means. People can join studies and trials before classic symptoms appear, which may be the only way to test treatments meant to prevent them. Splitting syndrome from biology also handles the fact that outward signs often fail to match the true underlying process. She notes the diseases can begin decades before symptoms, and that patients may carry more than one process at once.
Catalog record
| CREATOR | Kathleen L Poston |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |