Association between markers of brain pathology and verbal memory binding in autosomal dominant Alzheimer’s disease

Mario A Parra‐Rodriguez, Ana Y Baena, Diana Munera, Alex L Badillo‐Cabrera, Nikole A Bonillas Félix, Francisco Lopera, Yakeel T. Quiroz · 2025

Read Association between markers of brain pathology and verbal memory binding in autosomal dominant Alzheimer’s disease by Mario A Parra‐Rodriguez, Ana Y Baena, Diana Munera, Alex L Badillo‐Cabrera, Nikole A Bonillas Félix, Francisco Lopera, Yakeel T. Quiroz (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11715877.txt.

Description

Mario Parra-Rodriguez and co-authors test whether a word-binding memory task tracks brain disease markers in families with inherited Alzheimer's, in a 2025 study. Some Colombian families carry a gene that brings dementia early and with near certainty. Simple tests that flag the disease years ahead would aid trials and care planning.

The Memory Binding Test asks people to learn word pairs, stressing the mental glue that Alzheimer's loosens first. Scores were compared with brain scans that measure amyloid and tau, the disease's signature proteins. The team also asked whether test results separate gene carriers headed for dementia from non-carriers of the same age. A cheap paper test tied to scan biology could screen large at-risk groups.

Catalog record

CREATORMario A Parra‐Rodriguez, Ana Y Baena, Diana Munera, Alex L Badillo‐Cabrera, Nikole A Bonillas Félix, Francisco Lopera, Yakeel T. Quiroz
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE2 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11715877

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