A genome‐wide association study for clinical dementia phenotypes in an ethnoracially diverse cohort
Shraddha Sapkota, Marcio A Almeida, Lee‐Way Jin, Sarah Tomaszewski Farias, Charles Decarli · 2025
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Description
Shraddha Sapkota and co-authors search for genes linked to dementia in this 2025 study. Most gene studies of dementia have used people of European ancestry. Yet dementia rates are higher in African American and Hispanic groups, who are less often in such studies.
The team used a cohort of older adults from the University of California, Davis center. The group held 1,014 people classed as normal, mildly impaired, or demented. They scanned millions of gene variants and checked known Alzheimer risk sites. Most ancestry in the group was European, with African and Amerindian parts. No strong new gene links stood out.
Catalog record
| CREATOR | Shraddha Sapkota, Marcio A Almeida, Lee‐Way Jin, Sarah Tomaszewski Farias, Charles Decarli |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |