Modelling Small Vessel Disease Using Regional MRI Markers, and Mediating Effects on Cognitive Decline
Sokratis Charisis, Tanweer Rashid, Christina S. Dintica, Mitzi M. Gonzales, Hangfan Liu, Jeffrey B. Ware, Thomas R. Austin, Paul N. Jensen, Alison E Fohner, Jordan E. Tanley, Jingzhong Ding, José A. Luchsinger, Bonnie C. Sachs, Ilya M. Nasrallah, R Nick Bryan, Kathleen M. Hayden, David A Wolk, Katya · 2025
Read Modelling Small Vessel Disease Using Regional MRI Markers, and Mediating Effects on Cognitive Decline by Sokratis Charisis, Tanweer Rashid, Christina S. Dintica, Mitzi M. Gonzales, Hangfan Liu, Jeffrey B. Ware, Thomas R. Austin, Paul N. Jensen, Alison E Fohner, Jordan E. Tanley, Jingzhong Ding, José A. Luchsinger, Bonnie C. Sachs, Ilya M. Nasrallah, R Nick Bryan, Kathleen M. Hayden, David A Wolk, Katya (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11715843.txt.
Description
Sokratis Charisis and a large team model cerebral small vessel disease using regional MRI markers, in a study published in two thousand twenty-five. Small vessel disease damages the brain's tiny blood vessels and contributes to cognitive decline. The authors ask whether the location of its MRI markers changes what those markers mean.
Working with 891 participants from the Multi-Ethnic Study of Atherosclerosis, they segmented enlarged perivascular spaces, white matter hyperintensities, and microbleeds. Deep learning algorithms did the segmentation automatically. They also measured white matter microstructure from diffusion imaging. The team then tested links between marker patterns and cognition. They further examined whether these markers carry the effects of age and cardiovascular risk.
Catalog record
| CREATOR | Sokratis Charisis, Tanweer Rashid, Christina S. Dintica, Mitzi M. Gonzales, Hangfan Liu, Jeffrey B. Ware, Thomas R. Austin, Paul N. Jensen, Alison E Fohner, Jordan E. Tanley, Jingzhong Ding, José A. Luchsinger, Bonnie C. Sachs, Ilya M. Nasrallah, R Nick Bryan, Kathleen M. Hayden, David A Wolk, Katya |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |