Developing a novel brain‐based biomarker of mild cognitive impairment using time‐domain functional near‐infrared spectroscopy

Julien Dubois, Ryan M Field, Sami Jawhar, Erin M Koch, Zahra M. Aghajan, Naomi Miller, Katherine L Perdue, Moriah Taylor · 2025

Read Developing a novel brain‐based biomarker of mild cognitive impairment using time‐domain functional near‐infrared spectroscopy by Julien Dubois, Ryan M Field, Sami Jawhar, Erin M Koch, Zahra M. Aghajan, Naomi Miller, Katherine L Perdue, Moriah Taylor (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11715828.txt.

Description

Julien Dubois and co-authors develop a brain-based marker for mild cognitive impairment using a light-based scanning method, in a 2025 paper. Mild cognitive impairment is often missed in primary care. Early detection matters because support and planning work best early. The method, time-domain functional near-infrared spectroscopy, shines harmless light through the scalp to read brain activity.

Patients and healthy older adults took part in rest and task recordings. Tasks included naming words by category and by first sound. The team searched the signals for patterns that separate the groups. A reliable marker could give clinics a quick, objective screen. The device suits office settings better than large scanners. Further work must confirm accuracy in larger samples.

Catalog record

CREATORJulien Dubois, Ryan M Field, Sami Jawhar, Erin M Koch, Zahra M. Aghajan, Naomi Miller, Katherine L Perdue, Moriah Taylor
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE3 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11715828

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