Correlations between monoaminergic biomarkers, classical biomarkers and the BPSD‐DSII behavioral scale in Down individuals with and without Alzheimer's dementia
Charlotte Jacob, Hanane Kachar, Annelies Heylen, Marleen Tollenaere, Inge M.W. Verberk, Charlotte Teunissen, Peter Paul De Deyn, Debby Van Dam · 2025
Read Correlations between monoaminergic biomarkers, classical biomarkers and the BPSD‐DSII behavioral scale in Down individuals with and without Alzheimer's dementia by Charlotte Jacob, Hanane Kachar, Annelies Heylen, Marleen Tollenaere, Inge M.W. Verberk, Charlotte Teunissen, Peter Paul De Deyn, Debby Van Dam (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11715810.txt.
Description
Charlotte Jacob and seven co-authors look for links between blood chemistry, behavior changes, and dementia in people with Down syndrome, in this 2025 study. People with Down syndrome face a high risk of Alzheimer's disease, but the timing of decline varies a lot. A behavior scale filled in by caregivers is one early warning tool, and the team compared its scores with blood markers.
The blood panel covered brain signaling chemicals such as dopamine and serotonin, plus standard Alzheimer's markers. Early data suggest ties between parts of the behavior scale and some of these measures. The authors aim to learn whether a blood test could back up caregiver reports when judging if dementia is starting. That would support better daily care and earlier planning for families.
Catalog record
| CREATOR | Charlotte Jacob, Hanane Kachar, Annelies Heylen, Marleen Tollenaere, Inge M.W. Verberk, Charlotte Teunissen, Peter Paul De Deyn, Debby Van Dam |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |