Prevalence of cerebrospinal fluid AT biomarker profiles according to APOE genotype and across age in persons without dementia
Jolien van der Velden, Stephanie J. B. Vos, Betty M. Tijms, Julie Elisabeth Oomens, Nancy N Maserejian, Pieter Jelle Visser, Willemijn J. Jansen, Amyloid Biomarker Study Group · 2025
Read Prevalence of cerebrospinal fluid AT biomarker profiles according to APOE genotype and across age in persons without dementia by Jolien van der Velden, Stephanie J. B. Vos, Betty M. Tijms, Julie Elisabeth Oomens, Nancy N Maserejian, Pieter Jelle Visser, Willemijn J. Jansen, Amyloid Biomarker Study Group (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11715771.txt.
Description
Jolien van der Velden and co-authors, working with the Amyloid Biomarker Study Group, published this research paper in 2025. The team asked how often Alzheimer's-linked fluid patterns appear in people who do not have dementia. They sorted spinal fluid results by age and by gene type, since genes shape who is most at risk.
The study drew on 45 earlier studies and more than 8,000 people with normal thinking or mild memory loss. Each person was placed in one of four groups based on two fluid markers, one for amyloid and one for tau. The results show how these patterns shift with age and with each gene type. That map can help doctors plan ways to slow the disease before clear signs appear.
Catalog record
| CREATOR | Jolien van der Velden, Stephanie J. B. Vos, Betty M. Tijms, Julie Elisabeth Oomens, Nancy N Maserejian, Pieter Jelle Visser, Willemijn J. Jansen, Amyloid Biomarker Study Group |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 2 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |