The role of the insula predicting memory performance in Alzheimer's disease amyloid positive and negative: a clinical cohort study

Michelle M Coleman, Marc W Haut, Camila Vieira de Ligo Teixeira, Cierra M Keith, Rashi Mehta, Holly Phelps, Melanie Ward, Mark Miller, R Osvaldo Navia, Gary D Marano, Xiaofei Wang, Stephanie Pockl, Nafiisah Rajabalee, William T McCuddy, Pierre‐Francois D’Haese, Kirk Wilhelmson · 2025

Read The role of the insula predicting memory performance in Alzheimer's disease amyloid positive and negative: a clinical cohort study by Michelle M Coleman, Marc W Haut, Camila Vieira de Ligo Teixeira, Cierra M Keith, Rashi Mehta, Holly Phelps, Melanie Ward, Mark Miller, R Osvaldo Navia, Gary D Marano, Xiaofei Wang, Stephanie Pockl, Nafiisah Rajabalee, William T McCuddy, Pierre‐Francois D’Haese, Kirk Wilhelmson (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11715680.txt.

Description

Michelle Coleman and co-authors study in 2025 whether a deep brain area tied to feeling helps predict memory scores in Alzheimer's disease. Known waste linked areas shrink in the illness, but recent work hints this area, the insula, also plays a part in memory.

The team looked back at scans and memory tests for one hundred sixty one patients with mild loss or full illness, plus forty one healthy peers. They split patients by whether the waste marker was present or absent. Shape measures of the insula and known areas were then matched to word list recall, to test if the insula adds news the known areas miss.

Catalog record

CREATORMichelle M Coleman, Marc W Haut, Camila Vieira de Ligo Teixeira, Cierra M Keith, Rashi Mehta, Holly Phelps, Melanie Ward, Mark Miller, R Osvaldo Navia, Gary D Marano, Xiaofei Wang, Stephanie Pockl, Nafiisah Rajabalee, William T McCuddy, Pierre‐Francois D’Haese, Kirk Wilhelmson
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE3 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11715680

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