The relationship between neighborhood disadvantage and the brain age gap
Yolana C Martin, Nagesh Adluru, Veena A. Nair, Vivek Prabhakaran, Andrew L Alexander, Sterling C. Johnson, Sanjay Asthana, W. Ryan Powell, Amy J.H. Kind, Barbara B. Bendlin · 2025
Read The relationship between neighborhood disadvantage and the brain age gap by Yolana C Martin, Nagesh Adluru, Veena A. Nair, Vivek Prabhakaran, Andrew L Alexander, Sterling C. Johnson, Sanjay Asthana, W. Ryan Powell, Amy J.H. Kind, Barbara B. Bendlin (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11715659.txt.
Description
Yolana C Martin and co-authors ask whether living in a deprived neighborhood is linked to faster brain aging. Published in 2025, the study used brain scans from 1,052 people in Wisconsin cohorts tied to Alzheimer's research. A deep learning model estimated each brain's age, and the gap between that age and real age was the main measure.
Home addresses were matched to a state index of neighborhood disadvantage built from 17 signs of poverty, schooling, work, and surroundings. The most deprived fifth had a mean brain age gap of about one year, against about a quarter year for the rest. The gap was not firm by standard tests, and the authors note the study had low power.
Catalog record
| CREATOR | Yolana C Martin, Nagesh Adluru, Veena A. Nair, Vivek Prabhakaran, Andrew L Alexander, Sterling C. Johnson, Sanjay Asthana, W. Ryan Powell, Amy J.H. Kind, Barbara B. Bendlin |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |